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Printable Version Vincristine

Active Ingredients: Vincristine
Other Names: Oncovin, Vincasar
Drug Class: Mitotic Inhibitors
Rx Status: Available by prescription only
Generic Available: Yes
Product Images & Descriptions:

What is/are Vincristine?
What should I tell my health care providers before I take this medicine?
How should I use this medicine?
What if I miss a dose?
What may interact with this medicine?
What side effects may I notice from this medicine?
What should I watch for while using this medicine?
Where should I keep this medicine?

What is/are Vincristine? (Back to top)
VINCRISTINE is a chemotherapy drug. It slows the growth of cancer cells. This medicine is used to treat many types of cancer like Hodgkin's disease, leukemia, non-Hodgkin's lymphoma, neuroblastoma (brain cancer), rhabdomyosarcoma, and Wilms' tumor. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.


What should I tell my health care providers before I take this medicine? (Back to top)
They need to know if you have any of these conditions:

  • blood disorders
  • gout
  • infection (especially chickenpox, cold sores, or herpes)
  • kidney disease
  • liver disease
  • lung disease
  • nervous system disease like Charcot-Marie-Tooth (CMT)
  • recent or ongoing radiation therapy
  • an unusual or allergic reaction to vincristine, other chemotherapy agents, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine? (Back to top)
This drug is given as an infusion into a vein. It is administered in a hospital or clinic by a specially trained health care professional. If you have pain, swelling, burning, or any unusual feeling around the site of your injection, tell your health care professional right away.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.


What if I miss a dose? (Back to top)
It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.


What may interact with this medicine? (Back to top)
Do not take this medicine with any of the following:

  • itraconazole
  • mibefradil
  • voriconazole

This medicine may also interact with the following:
  • cyclosporine
  • erythromycin
  • fluconazole
  • ketoconazole
  • medicines for HIV like delavirdine, efavirenz, nevirapine
  • medicines for seizures like ethotoin, fosphenotoin, phenytoin
  • medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim
  • other chemotherapy drugs like cisplatin, L-asparaginase, methotrexate, mitomycin, paclitaxel
  • pegaspargase
  • vaccines
  • zalcitabine, ddC

Talk to your doctor or health care professional before taking any of these medicines:
  • acetaminophen
  • aspirin
  • ibuprofen
  • ketoprofen
  • naproxen

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.


What side effects may I notice from this medicine? (Back to top)
Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • confusion or changes in emotions or moods
  • constipation
  • cough
  • mouth sores
  • muscle weakness
  • nausea and vomiting
  • pain, swelling, redness or irritation at the injection site
  • pain, tingling, numbness in the hands or feet
  • problems with balance, talking, walking
  • seizures
  • stomach pain
  • trouble passing urine or change in the amount of urine

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
  • diarrhea
  • hair loss
  • jaw pain
  • loss of appetite

This list may not describe all possible side effects.


What should I watch for while using this medicine? (Back to top)
Your condition will be monitored carefully while you are receiving this medicine. You will need important blood work done while you are taking this medicine.

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself.

Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.

Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.

Men may have a lower sperm count while taking this medicine. Talk to your doctor if you plan to father a child.


Where should I keep this medicine? (Back to top)
This drug is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.


Last Updated:April 04, 2008

COPYRIGHT© Gold Standard, An Elsevier Company


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.

  Additional Information

  Check Drug Interactions with Vincristine

  Learn how Vincristine is/are used to treat:
  • Cancer

      Test Yourself! If you currently take Vincristine, do you know everything that you need to know?

      Make your own printable Medication / Emergency Contact Card



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